The 2022 Mercedes-Benz E 450 has 5 NHTSA recall campaigns affecting an estimated 263,782 vehicles. Recall repairs are always free at any authorized dealer. Owners have filed 16 complaints with NHTSA, most often about the electrical system. Last updated July 5, 2026.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.
Consequence
An overheated ground cable increases the risk of a fire.
Remedy
Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Consequence
A loss of drive power can increase the risk of a crash.
Remedy
Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at…
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Consequence
A loss of drive power can increase the risk of a crash.
Remedy
Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features…
Consequence
The inability to operate safety features (eCall system, hazard lights, electric seats, or automatic door locks) can increase the risk of injury during a crash.
Remedy
Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.
STEERING22V1890002022-03-258,396 affected
Defect
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the…
Consequence
Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
Remedy
Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.
Verbatim reports filed with NHTSA, lightly edited for readability and with personal
information removed.
“When turning the steering to maximum wheel camber, the wheel rims roll over the sidewall of the oem low-profile pirelli tires, damaging the tires and causing bubbling in the sidewall. This happens at a negligible speed, such as exiting a parking space. This vehicle is 3+ years old with 15k miles.…”
“Twice within a year a "48 voltage battery malfunction" warning appeared on my dashboard. Then a red warning light appears and I had about 30 seconds to find a safe place to pull over as loss of power causes deceleration of the vehicle . The cause, according to the diagnostic test performed by 2…”
“Twice within a year a "48 voltage battery malfunction" warning appeared on my dashboard. Then a red warning light appears and I had about 30 seconds to find a safe place to pull over as loss of power causes deceleration of the vehicle . The cause, according to the diagnostic test performed by 2…”
“An underbody splash shield (one of three, I believe), covering the transmission (the middle of the three) detached at highway speed and fell off the vehicle. This caused the leading edge of another shield to detach, which then, due to air flow, began dragging the highway. It was quite a noise;…”
“There is a recall on my vehicle for over 4 months now. I keep going/contacting the local dealers about the issue and they keep telling me to come back in a month and every time they tell me there is no remedy yet and they dont know when exactly they will be able to fix it. And according to nhtsa…”
“The contact owns a 2022 mercedes benz e450. The contact received notification of nhtsa campaign number: 23v445000 (fuel system, gasoline) however, the part to do the recall repair was not yet available. The local dealer was made aware of the issue and confirmed that parts were not yet available.…”
“The contact owns a 2022 mercedes-benz e450. The contact received notification of nhtsa campaign number: 23v445000 (fuel system, gasoline) however, the part to do the recall repair was unavailable. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall…”
“The contact owns a 2020 mercedes-benz e450. The contact stated that on three occasions the driver's side front seat independently adjusted when the vehicle was started. On another occasion, the vehicle started by independently. Additionally, the head-up projected display moved up the windshield…”
Recall, complaint, and investigation records from official NHTSA datasets (FLAT_RCL,
FLAT_CMPL, FLAT_INV), synced weekly. Counts reflect NHTSA records for the 2022 Mercedes-Benz E 450 as of
July 5, 2026. Complaint narratives are consumer-submitted and unverified. This page
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